Detalhe da pesquisa
1.
Receptor homodimerization plays a critical role in a novel dominant negative P2RY12 variant identified in a family with severe bleeding.
J Thromb Haemost
; 16(1): 44-53, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29117459
2.
Internalization and desensitization of the oxytocin receptor is inhibited by Dynamin and clathrin mutants in human embryonic kidney 293 cells.
Mol Endocrinol
; 20(2): 379-88, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16179383
3.
Rare platelet GPCR variants: what can we learn?
Br J Pharmacol
; 172(13): 3242-53, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25231155
4.
Morphine-induced internalization of the L83I mutant of the rat µ-opioid receptor.
Br J Pharmacol
; 172(2): 593-605, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24697554
5.
The effect of inhibitors of receptor internalization on the desensitization and resensitization of three Gs-coupled receptor responses.
Br J Pharmacol
; 125(7): 1594-600, 1998 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-9884089
6.
Enhanced expression of G protein-coupled receptor kinase 2 selectively increases the sensitivity of A2A adenosine receptors to agonist-induced desensitization.
Br J Pharmacol
; 125(2): 347-56, 1998 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-9786508
7.
Evidence for co-expression and desensitization of A2a and A2b adenosine receptors in NG108-15 cells.
Biochem Pharmacol
; 55(5): 595-603, 1998 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-9515570
8.
A novel mutation in the P2Y12 receptor and a function-reducing polymorphism in protease-activated receptor 1 in a patient with chronic bleeding.
J Thromb Haemost
; 12(5): 716-25, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24612435
9.
Platelet dysfunction associated with the novel Trp29Cys thromboxane A2 receptor variant.
J Thromb Haemost
; 11(3): 547-54, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23279270
10.
Deletion of the distal COOH-terminus of the A2B adenosine receptor switches internalization to an arrestin- and clathrin-independent pathway and inhibits recycling.
Br J Pharmacol
; 159(3): 518-33, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20128803
11.
Rapid resensitization of purinergic receptor function in human platelets.
J Thromb Haemost
; 6(8): 1393-404, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18513210
12.
Reciprocal regulation of platelet responses to P2Y and thromboxane receptor activation.
J Thromb Haemost
; 6(3): 534-43, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18088343
13.
Rapid genetic diagnosis of heritable platelet function disorders with next-generation sequencing: proof-of-principle with Hermansky-Pudlak syndrome.
J Thromb Haemost
; 10(2): 306-9, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22118648
14.
Selective regulation of endogenous G protein-coupled receptors by arrestins in HEK293 cells.
J Biol Chem
; 275(17): 12900-8, 2000 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-10777589
15.
A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization.
Mol Pharmacol
; 51(6): 991-8, 1997 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-9187265
16.
Characterization of G protein-coupled receptor regulation in antisense mRNA-expressing cells with reduced arrestin levels.
Biochemistry
; 38(27): 8723-32, 1999 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-10393547
17.
Agonist-induced internalization of the metabotropic glutamate receptor 1a is arrestin- and dynamin-dependent.
J Neurochem
; 78(3): 546-51, 2001 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-11483657
18.
Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization.
J Biol Chem
; 274(43): 31076-86, 1999 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-10521508
19.
Rapid agonist-induced desensitization and internalization of the A(2B) adenosine receptor is mediated by a serine residue close to the COOH terminus.
J Biol Chem
; 276(32): 30199-207, 2001 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-11333255
20.
Arrestin isoforms dictate differential kinetics of A2B adenosine receptor trafficking.
Biochemistry
; 39(42): 12828-36, 2000 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-11041847